Nutramax Laboratories Avmacol Extra Strength #1 Researched Sulforaphane-Producing Brand for Detoxification, Antioxidant Support, Immune Health, Adults & Children, Moringa, 75 Tablets
Nutramax Laboratories Avmacol Extra Strength #1 Researched Sulforaphane-Producing Brand for Detoxification, Antioxidant Support, Immune Health, Adults & Children, Moringa, 75 Tablets
#1 RESEARCHED SULFORAPHANE BRAND^: Avmacol is the most clinically studied supplement of its kind, used in more human trials than any other
FORMULATED TO PROMOTE DETOXIFICATION*: Features a unique blend of broccoli seed and sprout extract (ERS92) for glucoraphanin, plus Myrosimax® myrosinase enzyme with moringa. Enhanced with beta-glucan and maitake mushroom extract to aid the body’s natural detox processes*
IMMUNE HEALTH FORMULATION: Includes maitake mushroom extract with beta-glucan, designed to help maintain healthy immune cell function
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Vegetarian
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Gluten-Free
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No Generic Equivalent
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Packaged in BPA-free bottles
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Subject to more than 80 quality checks
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Vegetarian
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Gluten-Free
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No Generic Equivalent
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Packaged in BPA-free bottles
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Subject to more than 80 quality checks
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Validated with human research
Our exclusive Sulforaphane Production System® is validated in humans by measuring metabolites of sulforaphane collected in the urine.
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The choice for clinical studies
Because of the Sulforaphane Production System® exclusive to Avmacol®, numerous researchers have chosen this product for clinical studies worldwide
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Promotes natural detoxification
Sulforaphane promotes your body’s natural detoxification process for certain environmental threats.
Directions for Use
Take one (1) tablet per day with a meal. If you have a condition that requires medical attention always consult your physician before taking any dietary supplement.
Directions for Use
Take one (1) tablet per day with a meal. If you have a condition that requires medical attention always consult your physician before taking any dietary supplement.
Why choose Awmacol EXTRA STRENGTH ？
Patented, shelf-stable,and tableted formula
Contains glucoraphanin +active myrosinase enzyme
Supportsimmune health withadded beta-glucan*
Combination ofingredients worksbetter than sulforaphane alone*
Why Can't I Just Eat Broccoli?
Since sulforaphane is associated with cruciferous vegetables, namely broccoli and broccoli sprouts, many people think they can get the benefits of sulforaphane just by eating their vegetables. Unfortunately, it isn’t that simple, as sulforaphane itself is not found in broccoli. Rather it is the essential ingredients, glucoraphanin and myrosinase, that are present. Unfortunately, there may not be enough of either compound in the plant to allow for adequate sulforaphane production. This can be due to seed quality, soil composition, the age of the plant, and many other factors.
Additionally, any myrosinase enzyme that is present in the plant can be destroyed during the cooking process. So while glucoraphanin and the myrosinase enzyme can be found in the vegetables you eat, the ones you buy from the market are not necessarily reliable sources of either compound.
What is Avmacol® Extra Strength?
Avmacol® Extra Strength is a patented, sulforaphane-producing supplement that works in combination with Maitake mushroom extract (containing beta-glucans) to support your body's natural detoxification process better than sulforaphane alone.1Avmacol® Extra Strength provides glucoraphanin, also known as sulforaphane glucosinolate, and active myrosinase enzyme, which are the essential ingredients needed for sulforaphane production. Without active myrosinase enzyme, one may not be able to reap sulforaphane’s many health-promoting benefits.
How Maitake Mushroom Extract Works in Combination with Sulforaphane
The Maitake mushroom extract (containing beta-glucans) works in combination with sulforaphane to support your body’s natural detoxification process better than sulforaphane alone.1In addition, the Maitake mushroom extract found in Avmacol® Extra Strength provides the added bonus of immune support by promoting neutrophil function and natural killer cell activity.
The Science Behind Avmacol®Extra Strength
The combination of sulforaphane and Maitake extract supports the movement (or translocation) from the cytoplasm to the nucleus of NRF2 and increases the levels of certain Phase 2 enzymes. Below are images of a technique called immunofluorescence which illustrate how much protein is being produced in the cell and the location of that protein.
In control cells (left panel), the green staining indicates that NRF2 remains largely in the cytoplasm (arrows) without much protein located in the nucleus, which is counter-stained in blue. When cells are exposed to sulforaphane and Maitake (right panel), NRF2 moves to the nucleus (arrows) where it can bind to DNA to turn on expression of certain Phase 2 enzymes.
Sulforaphane and Maitake Extract Boosts Select Phase 2 Enzyme Production Including NQO1 and HO-1
NQO1 Protein Expression in THLE2 Liver Cells
In control cells (left panel) NQO1 protein expression is indicated by the green staining. When cells are exposed to sulforaphane and Maitake (right panel), the level of NQO1 staining, representing the amount of protein, is increased.
Sulforaphane and Maitake Extract Boosts Select Phase 2 Enzyme Production Including NQO1 and HO-1
NQO1 Protein Expression in THLE2 Liver Cells
In control cells (left panel) NQO1 protein expression is indicated by the green staining. When cells are exposed to sulforaphane and Maitake (right panel), the level of NQO1 staining, representing the amount of protein, is increased.
Sulforaphane and Maitake Extract Boosts Select Phase 2 Enzyme Production Including NQO1 and HO-1
NQO1 Protein Expression in THLE2 Liver Cells
In control cells (left panel) NQO1 protein expression is indicated by the green staining. When cells are exposed to sulforaphane and Maitake (right panel), the level of NQO1 staining, representing the amount of protein, is increased.
HO-1 Protein Expression in THLE2 Liver Cells
In control cells (left panel) HO-1 protein expression is indicated by the green staining. When cells are exposed to sulforaphane and Maitake (right panel), the level of HO-1 staining, representing the amount of protein, is increased.
HO-1 Protein Expression in THLE2 Liver Cells
In control cells (left panel) HO-1 protein expression is indicated by the green staining. When cells are exposed to sulforaphane and Maitake (right panel), the level of HO-1 staining, representing the amount of protein, is increased.
Who Would Benefit from Avmacol® Extra Strength?
We are capable of incredible things; and when our bodies get the support they need, the results can be amazing. Avmacol® unleashes the power of broccoli to help your body fight off toxin-related stress at the cellular level.
How Avmacol® Extra Strength Work?
OurSulforaphane Production System®supplies broccoli seed extract (glucoraphanin) and Myrosimax® (Active Myrosinase Enzyme) which helps promote sulforaphane production in your body. As depicted in the diagram below, when sulforaphane enters your cells it allows for a master regulator, known as NRF2, to enter the nucleus and bind to DNA. This helps increase the production of important Phase 2 detoxifying enzymes, promoting your body’s natural detoxification process, thereby supporting the elimination of potentially harmful metabolites.*
The Importance of Active Myrosinase Enzyme
The conversion of glucoraphanin to sulforaphane can be expressed in this simple equation:
Avmacol® and Sulforaphane
